Zantac is one of the first drugs to achieve $I billion in sales, but research is now showing that it has a dark side that might have hurt many patients. The drug has been found to have N-Nitrosodimethylamine (NDMA) in levels higher than the recommended daily intake by the FDA.
NDMA is a nitrosamine impurity that is linked to cancer. So, if you are one of those who have developed cancer after using the drug for long, then you have a right to file a lawsuit against drug manufacturers. Let us expound more on what you should know about filing a Zantac lawsuit
What is Zantac?
Zantac is a brand name for ranitidine. The drug was first introduced into the market in 1980 by GlaxoSmithKline. Companies like Boehringer, Ingelheim and Sanofi also started manufacturing the drug until recently. Ranitidine is sold over the counter around the world and it is in the class of drugs referred to as histamine-2 receptor blockers. The action of ranitidine is inhibition of histamine action in the gastric parietal cells by histamine H2 receptors. This way, ranitidine has often been used to decrease the production of stomach acids. The common Zantac dosage is 150mg tablets twice daily or 300mg once daily where it is used in the treatment, relieving and prevention of conditions like:
- Gastroesophageal reflux disease( GERD)
- Different types of ulcers ( Peptic, duodenal, gastric and stress-induced)
- Upper gastrointestinal bleeding,
- Erosive esophagitis
- Zollinger-Ellison syndrome
The long-term side effects of Ranitidine
Other than cancer, there are several long-term side effects you can suffer from after taking Zantac. They include reduced function of the liver, lungs, and kidney, jaundice, hepatitis, tachycardia, cardiac arrhythmia, and Vitamin B-12 deficiency, to mention but a few. The bottom line is that the drug is not safe to use. You should file a Zantac lawsuit if you have developed cancer owing to prolonged use of the drug. As a matter of fact, manufacturers have long known the risks of the drug and yet they still continued producing the drug for financial gain.
Research has linked Zantac to cancer
Since 1980, when the drug was introduced into the market, several studies have shown that it is linked to different types of cancer. They include stomach cancer, cancer of the large and small intestines, bladder cancer, kidney cancer, and colorectal cancer, etc.
Journal Carcinogenesis published a study indicating that persons who consumed Ranitidine, were found to have a spike of NDMA concentration in urine. The increase is also related to schistosomiasis, a condition where N-nitrosamines are connected to diagnosis with bladder cancer. The National Cancer Institute conducted a similar study in 2014. They found that the ingestion of NDMA has a potential bladder cancer risk.
In 2017, Journal Chemosphere published a study stating that when ranitidine is placed in water, it forms NDMA. On September 13, 2019, the U.S Food and Drugs Administration stated that they had started investigating Zantac as a risk for cancer. This was after they tested 150 tablets of Zantac and found that the daily intake limit was exceeded. The recommended maximum daily intake is 96 nanograms. However, the drugs were found to contain 2.5-3 million nanograms. This was equivalent to 26,000- 31,000 times greater than the recommended intake.
According to research, even on the ingestion of a normal dose of ranitidine, ranitidine chloride is metabolized into NDMA. Therefore, by design, ranitidine reacts with the body to produce NDMA, the cancer-causing agent that is now hurting many.
The U.S Food and Drugs Administration, on April 1, 2020, announced that there should be a total withdrawal of Zantac from the market. The withdrawal was after a determination that NDMA in Ranitidine increases over time after storage in temperature above the room temperatures. The classification of Zantac as a cancer risk was also supported by the World Health Organization (WHO) and the Environmental Protection Agency (EPA).
Even before the directive by the FDA to recall Zantac, a number of manufacturers had already started recalling the drug. This was triggered by a warning from the FDA against the drug, on September 13, 2019. Pharmaceutical companies like Valisure and Emery Pharma had earlier done tests on the drug and found high levels of NDMA. They petitioned with the FDA asking them to suspend the sales of ranitidine and recall whatever is already in the market. Manufacturers are now working hard, recalling the drug from the market.
Filing a lawsuit
Cancer can cause pain and suffering, and death. If you or your loved one used Zantac and developed cancer, then you need to file a lawsuit to get the compensation you certainly deserve from the unscrupulous manufacturers. Manufacturers already knew that the drug had the potential to cause cancer but still let it to the market for their financial gain. You will need to work with an experienced attorney who can help you get compensation for damages, pain, suffering, and loss of loved ones.
In a nutshell, Zantac has the potential of causing cancer, among other medical effects. Cancer is known to cause suffering, pain, and loss of wages and finances and death. Do not suffer because of the greed and mistakes on the side of manufacturers. Seek help from an experienced attorney to help file a lawsuit and protect your rights.